Senior Manager, DMPK Project Leader

We Are Teva

We’re Teva, a leading innovative biopharmaceutical company, enabled by a world-class generics business. Whether it’s innovating in the fields of neuroscience and immunology or delivering high-quality medicine worldwide, we’re dedicated to addressing patients’ needs now and in the future. Here, you will be part of a high-performing, inclusive culture that values fresh thinking and collaboration. You'll have the room to grow, the flexibility to balance life with work, and the opportunity to better health worldwide, together.

Our Team, Your Impact

We are seeking a highly motivated and experienced DMPK Project Leader to join our dynamic R&D team. This individual will lead DMPK strategy and execution across a diverse portfolio, including small molecules for movement disorders, neurodegenerative diseases and biologics such as monoclonal and bispecific antibodies. The ideal candidate will bring deep scientific expertise, strategic thinking, and cross-functional leadership to advance our drug discovery and development programs.

How You’ll Spend Your Day

• Design, oversee, and interpret in vitro and in vivo ADME/PK studies, including studies tailored to the unique properties of small molecules and biologicals.
• Data Analysis and Modeling: Analyze and interpret PK/TOX and ADME data using industry-standard tools, including human PK predictions and clinical translation, to inform drug development decisions
• CRO Management and Oversight: Build strong relationships with external CROs, ensuring study quality, compliance with regulatory standards, and alignment with IND-enabling requirements
• Author and review DMPK sections of regulatory documents and respond to regulatory agency queries as a subject matter expert.
• Cross-Functional Collaboration: Collaborate closely with discovery, toxicology, pharmacology and early clinical teams, to provide guidance on PK/TOX strategies and data interpretation, enhancing overall drug discovery efforts
• Innovation and Technology Integration: Work with early and preclinical development teams to integrate cutting-edge technologies and methodologies, driving the innovation of PK and toxicology assessments to expand the drug discovery pipeline

Your Skills and Experience

• PhD in Pharmaceutical Sciences, Medicinal Chemistry or related field.
• Minimum 4 years of industry experience in DMPK, with a proven track record in small molecule and biologic drug development.
• Expertise in drug metabolism and impact on drug-drug interaction potential is highly desirable
• Understanding of monoclonal and bispecific antibody pharmacokinetics, including FcRn interactions, target-mediated drug disposition, and immunogenicity considerations.
• Experience with regulatory submissions and GLP-compliant studies.
• Excellent communication skills with the ability to present complex data to diverse audiences.
• Collaborative approach and project management skills.

Also Good to Have

• Familiarity with bioanalytical assay development for both small and large molecules.
• Prior involvement in first-in-human studies and clinical pharmacology planning.
• Experience in regulatory support of marketed products and life-cycle management  

How We’ll Take Care of You

At Teva, better health starts from within, and that includes you. From day one, you’ll be supported with benefits designed to help you thrive in and out of work. This includes generous annual leave, reward plans, flexible working schedules (dependent on role), access to tailored health support, and meaningful ways to give back to the community.  When it comes to your career, you’ll be encouraged to explore, evolve, and shape your path. Twist, our one-stop shop for career development platform, gives you access to a wide range of possibilities, from learning programs and short-term projects to opportunities for internal growth. Here, you’ll be part of a culture that empowers you to reach your goals and prioritize your wellbeing every step of the way. 

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Teva’s Equal Employment Opportunity Commitment

Teva Pharmaceuticals is committed to equal opportunity in employment. It is Teva's global policy that equal employment opportunity be provided without regard to age, race, creed, color, religion, sex, disability, pregnancy, medical condition, sexual orientation, gender identity or expression, ancestry, veteran status, national or ethnic origin or any other legally recognized status entitled to protection under applicable laws. We are committed to a diverse and inclusive workplace for all. If you are contacted for a job opportunity, please advise us of any accommodations needed to support you throughout the recruitment and selection process. All accommodation information provided will be treated as confidential and used only for the purpose of providing an accessible candidate experience.